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Number of items: 10.

Article

Hughes, Samantha J. and Millan, David S. and Kilty, Iain C. and Lewthwaite, Russell A. and Mathias, John P. and O’Reilly, Mark A. and Pannifer, Andrew and Phelan, Anne and Stühmeier, Frank and Baldock, Darren A. and Brown, David G. (2011) Fragment based discovery of a novel and selective PI3 kinase inhibitor. Bioorganic and Medicinal Chemistry Letters, 21 (21). pp. 6586-6590. ISSN 0960-894X. (The full text of this publication is not available from this repository)

Phillips, Chris and Roberts, Lee R. and Schade, Markus and Bazin, Richard and Bent, Andrew and Davies, Nichola L. and Moore, Rob and Pannifer, Andrew D. and Pickford, Andrew R. and Prior, Stephen H. and Read, Christopher M. and Scott, Andrew and Brown, David G. and Xu, Bin and Irving, Stephen L. (2011) Design and Structure of Stapled Peptides Binding to Estrogen Receptors. Journal of the American Chemical Society, 133 (25). pp. 9696-9699. ISSN 0002-7863. (The full text of this publication is not available from this repository)

Luban, Jeremy and Blair, Wade S. and Pickford, Chris and Irving, Stephen L. and Brown, David G. and Anderson, Marie and Bazin, Richard and Cao, Joan and Ciaramella, Giuseppe and Isaacson, Jason and Jackson, Lynn and Hunt, Rachael and Kjerrstrom, Anne and Nieman, James A. and Patick, Amy K. and Perros, Manos and Scott, Andrew D. and Whitby, Kevin and Wu, Hua and Butler, Scott L. (2010) HIV Capsid is a Tractable Target for Small Molecule Therapeutic Intervention. PLoS Pathogens, 6 (12). e1001220. ISSN 1553-7374. (The full text of this publication is not available from this repository)

Owen, Dafydd R. and Walker, John K. and Jon Jacobsen, E. and Freskos, John N. and Hughes, Robert O. and Brown, David L. and Bell, Andrew S. and Brown, David G. and Phillips, Christopher and Mischke, Brent V. and Molyneaux, John M. and Fobian, Yvette M. and Heasley, Steve E. and Moon, Joseph B. and Stallings, William C. and Joseph Rogier, D. and Fox, David N.A. and Palmer, Michael J. and Ringer, Tracy and Rodriquez-Lens, Margarita and Cubbage, Jerry W. and Blevis-Bal, Radhika M. and Benson, Alan G. and Acker, Brad A. and Maddux, Todd M. and Tollefson, Michael B. and Bond, Brian R. and MacInnes, Alan and Yu, Yung (2009) Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors. Bioorganic & Medicinal Chemistry Letters, 19 (15). pp. 4088-4091. ISSN 0960894X. (Full text available)
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Bunnage, Mark E. and Blagg, Julian and Steele, John and Owen, Dafydd R. and Allerton, Charlotte M.N. and McElroy, Andrew B. and Miller, Duncan and Ringer, Tracy and Butcher, Ken and Beaumont, Kevin and Evans, Karen and Gray, Andrew J. and Holland, Stephen J. and Feeder, Neil and Moore, Robert S. and Brown, David G. (2007) Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis. Journal of medicinal chemistry, 50 (24). pp. 6095-6103. ISSN 0022-2623. (The full text of this publication is not available from this repository)

Fish, Paul V. and Barber, Christopher G. and Brown, David G. and Butt, Richard and Collis, Michael G. and Dickinson, Roger P. and Henry, Brian T. and Horne, Valerie A. and Huggins, John P. and King, Elizabeth and O'Gara, Margaret and McCleverty, Dawn and McIntosh, Fraser and Phillips, Christopher and Webster, Robert (2007) Selective Urokinase-Type Plasminogen Activator Inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines. Journal of Medicinal Chemistry, 50 (10). pp. 2341-51. ISSN 0022-2623 . (The full text of this publication is not available from this repository)

Palmer, Michael J. and Bell, Andrew S. and Fox, David N. A. and Brown, David G. (2007) Design of second generation phosphodiesterase 5 inhibitors. Current topics in medicinal chemistry, 7 (4). pp. 405-419. ISSN 1873-4294. (The full text of this publication is not available from this repository)

Knoechel, Thorsten R. and Tucker, Alec D. and Robinson, C. and Phillips, Chris and Taylor, Wendy and Bungay, Peter J. and Kasten, Shane A. and Roche, Thomas E. and Brown, David G. (2006) Regulatory roles of the N-terminal domain based on crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands. Biochemistry, 45 (2). pp. 402-415. ISSN 0006-2960. (The full text of this publication is not available from this repository)

Allerton, Charlotte M.N. and Barber, Christopher G. and Beaumont, Kevin C. and Brown, David G. and Cole, Susan M. and Ellis, David and Lane, Charlotte A.L. and Maw, Graham N. and Mount, Natalie M. and Rawson, David J. and Robinson, C. and Street, Stephen D.A. and Summerhill, Nicholas W. (2006) A Novel Series of Potent and Selective PDE5 Inhibitors with Potential for High and Dose-Independent Oral Bioavailability†. Journal of Medicinal Chemistry, 49 (12). pp. 3581-3594. ISSN 0022-2623. (The full text of this publication is not available from this repository)

O'Brien, Sean E. and Brown, David G. and Mills, James E. and Phillips, Chris and Morris, Gregg (2005) Computational Tools for the Analysis and Visualization of Multiple Protein-Ligand Complexes. Journal of Molecular Graphics and Modelling, 24 (3). pp. 186-194. ISSN 1093-3263. (The full text of this publication is not available from this repository)

This list was generated on Mon Apr 21 08:21:49 2014 BST.