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2018
Blaazer, Antoni R. and Singh, Abhimanyu K. and de Heuvel, Erik and Edink, Ewald and Orrling, Kristina M. and Veerman, Johan J. N. and van den Bergh, Toine and Jansen, Chimed and Balasubramaniam, Erin and Mooij, Wouter J. and Custers, Hans and Sijm, Maarten and Tagoe, Daniel N. A. and Kalejaiye, Titilola D. and Munday, Jane C. and Tenor, Hermann and Matheeussen, An and Wijtmans, Maikel and Siderius, Marco and de Graaf, Chris and Maes, Louis and de Koning, Harry P. and Bailey, David S. and Sterk, Geert Jan and de Esch, Iwan J. P. and Brown, David G. and Leurs, Rob (2018) Targeting a Subpocket in Trypanosoma brucei Phosphodiesterase B1 (TbrPDEB1) Enables the Structure-Based Discovery of Selective Inhibitors with Trypanocidal Activity. Journal of Medicinal Chemistry, 61 (9). pp. 3870-3888. ISSN 0022-2623. (doi:https://doi.org/10.1021/acs.jmedchem.7b01670) (Full text available) |