Oliveira-Campos, Ana M. F., Sivasubramanian, Aravind, Rodrigues, Lígia M., Seijas, Julio A., Pilar Vázquez-Tato, M., Peixoto, Francisco, Abreu, Carlos G., Cidade, Honorina, Oliveira, Ana, Pinto, Madalena and others. (2008) Substituted Pyrazolo[3,4-d]pyrimidines: Microwave-Assisted, Solvent-Free Synthesis and Biological Evaluation. Helvetica Chimica Acta, 91 (7). pp. 1336-1345. ISSN 0018-019X. (doi:10.1002/hlca.200890145) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:98389)
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Official URL: https://doi.org/10.1002/hlca.200890145 |
Abstract
A simple and efficient method has been developed for the synthesis of various pyrazolo[3,4-d]pyrimidines by using microwave irradiation under solvent-free conditions. The advantages of applying microwave irradiation compared with the classical method were demonstrated. The structures of all the compounds were confirmed by the usual techniques and, in two cases, by X-ray analysis. The compounds did not display appreciable ability to inhibit xanthine oxidase activity. Screening for antifungal activity showed that some derivatives were active against four fungi, with more significant results for Botrytis.
Item Type: | Article |
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DOI/Identification number: | 10.1002/hlca.200890145 |
Subjects: | R Medicine |
Divisions: | Divisions > Division of Natural Sciences > Kent and Medway Medical School |
Depositing User: | Ana Oliveira |
Date Deposited: | 27 Nov 2022 16:18 UTC |
Last Modified: | 02 Dec 2022 09:46 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/98389 (The current URI for this page, for reference purposes) |
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