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Attendance-related healthcare resource utilisation and costs in patients with Brugada Syndrome in Hong Kong: A retrospective cohort study

Lee, Sharen, Chung, Cheuk To, Chou, Oscar Hou In, Lee, Teddy Tai Loy, Radford, Danny, Jeevaratnam, Kamalan, Wong, Wing Tak, Cheng, Shuk Han, Mok, Ngai Shing, Liu, Tong, and others. (2023) Attendance-related healthcare resource utilisation and costs in patients with Brugada Syndrome in Hong Kong: A retrospective cohort study. Current Problems in Cardiology, 48 (2). Article Number 101513. ISSN 0146-2806. (doi:10.1016/j.cpcardiol.2022.101513) (KAR id:98219)

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Understanding healthcare resource utilisation and its associated costs are important for identifying areas of improvement regarding resource allocations. However, there is limited research exploring this issue in the setting of Brugada syndrome (BrS).


This was a retrospective territory-wide study of BrS patients from Hong Kong. Healthcare resource utilisation for accident and emergency (A&E), inpatient and specialist outpatient attendances were analysed over a 19-year period, with their associated costs presented in US dollars.


A total of 507 BrS patients with a mean presentation age of 49.9 ± 16.3 years old were included. Of these, 384 patients displayed spontaneous type 1 electrocardiographic (ECG) Brugada pattern and 77 patients had presented with ventricular tachycardia/ventricular fibrillation (VT/VF). At the individual patient level, the median annualised costs were $110 (52-224) at the (A&E) setting, $6812 (1982-32414) at the inpatient setting and $557 (326-1001) for specialist outpatient attendances. Patients with initial VT/VF presentation had overall greater costs in inpatient ($20161 [9147-189215] vs. $5290 [1613-24937],p<0.0001) and specialist outpatient setting ($776 [438-1076] vs. $542 [293-972],p=0.015) compared to those who did not present VT. In addition, patients without Type 1 ECG pattern had greater median costs in the specialist outpatient setting ($7036 [3136-14378] vs. $4895 [2409-10554],p=0.019).


There is a greater healthcare demand in the inpatient and specialist outpatient settings for BrS patients. The most expensive attendance type was inpatient setting stay at $6812 per year. The total median annualised cost of BrS patients without VT/VF presentation was 78% lower compared to patients with VT/VF presentation.

Item Type: Article
DOI/Identification number: 10.1016/j.cpcardiol.2022.101513
Uncontrolled keywords: Brugada syndrome; healthcare resource; utilisation costs
Subjects: R Medicine
Divisions: Divisions > Division of Natural Sciences > Kent and Medway Medical School
Funders: University of Kent (
SWORD Depositor: JISC Publications Router
Depositing User: JISC Publications Router
Date Deposited: 23 Nov 2022 14:43 UTC
Last Modified: 07 Mar 2023 11:59 UTC
Resource URI: (The current URI for this page, for reference purposes)
Lee, Sharen:
Chou, Oscar Hou In:
Wong, Wing Tak:
Liu, Tong:
Tse, Gary:
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