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Chemical ionisation mass spectrometry.

Mather, Roger E. (1979) Chemical ionisation mass spectrometry. Doctor of Philosophy (PhD) thesis, University of Kent. (doi:10.22024/UniKent/01.02.94513) (KAR id:94513)


Almost all of the work on chemical ionisation (Cl) mass spectrometry, reported to date, has been performed using the high pressure mass spectrometric technique in which the ion source is operated at a pressure of ca. 1 Torr. This work involves the development of an ion source, based on the three-dimensional quadrupole ion trap (QUISTOR), with which it is possible to perform Cl studies at pressures of ca. 10⁻⁵ Torr.

The characteristic features of the chemical ionisation process are first described in general terms and this is followed by a literature review of the instrumental aspects of chemical ionisation mass spectrometry. After a brief theoretical description of the Quistor an account is given of the physical characterisation of the device, which includes a study of the limits of stability and also ion loss and ejection processes.

This is followed by a description of the design, construction and characterisation of a Quistor-type ion source for a magnetic sector mass spectrometer and the use of this instrument to produce low pressure Cl mass spectra. The modification of the same type of mass spectrometer to operate in the high pressure Cl mode is then described, this includes the design and construction of a high pressure ion source and the sample and reagent gas introduction systems. Finally, the performance of the Quistor as a low pressure Cl ion source is compared with that of the high pressure Cl ion source.

Item Type: Thesis (Doctor of Philosophy (PhD))
DOI/Identification number: 10.22024/UniKent/01.02.94513
Additional information: This thesis has been digitised by EThOS, the British Library digitisation service, for purposes of preservation and dissemination. It was uploaded to KAR on 25 April 2022 in order to hold its content and record within University of Kent systems. It is available Open Access using a Creative Commons Attribution, Non-commercial, No Derivatives ( licence so that the thesis and its author, can benefit from opportunities for increased readership and citation. This was done in line with University of Kent policies ( If you feel that your rights are compromised by open access to this thesis, or if you would like more information about its availability, please contact us at and we will seriously consider your claim under the terms of our Take-Down Policy (
Subjects: Q Science > QD Chemistry
Divisions: Divisions > Division of Natural Sciences > Chemistry and Forensics
SWORD Depositor: SWORD Copy
Depositing User: SWORD Copy
Date Deposited: 14 Jul 2023 15:29 UTC
Last Modified: 14 Jul 2023 15:29 UTC
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