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Fungal interactions with the human host: exploring the spectrum of symbiosis

Hall, Rebecca A., Noverr, Mairi C (2017) Fungal interactions with the human host: exploring the spectrum of symbiosis. Current Opinion in Microbiology, 40 . pp. 58-64. ISSN 1369-5274. (doi:10.1016/j.mib.2017.10.020) (KAR id:91788)

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https://doi.org/10.1016/j.mib.2017.10.020

Abstract

Fungi are ubiquitous transient or persistent human colonisers, and form the mycobiome with shifts in niche specific mycobiomes (dysbiosis) being associated with various diseases. These complex interactions of fungal species with the human host can be viewed as a spectrum of symbiotic relationships (i.e. commensal, parasitic, mutualistic, amensalistic). The host relevant outcome of the relationship is the damage to benefit ratio, elegantly described in the damage response framework. This review focuses on Candida albicans, which is the most well studied human fungal symbiont clinically and experimentally, its transition from commensalism to parasitism within the human host, and the factors that influence this relationship.

Item Type: Article
DOI/Identification number: 10.1016/j.mib.2017.10.020
Subjects: Q Science > QR Microbiology
Divisions: Divisions > Division of Natural Sciences > Biosciences
Depositing User: Becky Hall
Date Deposited: 30 Nov 2021 11:54 UTC
Last Modified: 01 Dec 2021 13:50 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/91788 (The current URI for this page, for reference purposes)
Hall, Rebecca A.: https://orcid.org/0000-0002-4908-8168
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