Skip to main content

Dressed to impress: impact of environmental adaptation on the Candida albicans cell wall

Hall, Rebecca A. (2015) Dressed to impress: impact of environmental adaptation on the Candida albicans cell wall. Molecular Microbiology, 97 (1). pp. 7-17. ISSN 0950-382X. (doi:10.1111/mmi.13020) (KAR id:91785)

PDF Publisher pdf
Language: English

Download (3MB) Preview
[thumbnail of Hall 2015.pdf]
This file may not be suitable for users of assistive technology.
Request an accessible format
Official URL:


Candida albicans is an opportunistic fungal pathogen of humans causing superficial mucosal infections and life-threatening systemic disease. The fungal cell wall is the first point of contact between the invading pathogen and the host innate immune system. As a result, the polysaccharides that comprise the cell wall act as pathogen associated molecular patterns, which govern the host-pathogen interaction. The cell wall is dynamic and responsive to changes in the external environment. Therefore, the host environment plays a critical role in regulating the host-pathogen interaction through modulation of the fungal cell wall. This review focuses on how environmental adaptation modulates the cell wall structure and composition, and the subsequent impact this has on the innate immune recognition of C. albicans.

Item Type: Article
DOI/Identification number: 10.1111/mmi.13020
Uncontrolled keywords: Candida albicans
Subjects: Q Science > QR Microbiology
Divisions: Divisions > Division of Natural Sciences > Biosciences
Depositing User: Becky Hall
Date Deposited: 30 Nov 2021 11:37 UTC
Last Modified: 01 Dec 2021 14:08 UTC
Resource URI: (The current URI for this page, for reference purposes)
Hall, Rebecca A.:
  • Depositors only (login required):


Downloads per month over past year