Cytokinesis in fission yeast: a myosin pas de deux

Mulvihill, Daniel P. and Win, Thein Z. and Pack, Thomas P. and Hyams, Jeremy S. (2000) Cytokinesis in fission yeast: a myosin pas de deux. Microscopy Research and Technique, 49 (2). pp. 152-60. ISSN 1059-910X . (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Cytokinesis in the fission yeast, Schizosaccharomyces pombe consists of two distinct but overlapping events: the assembly and constriction of a cytokinetic actomyosin ring (CAR) and the formation of a cross wall or septum. These two processes must be spatially and temporally coordinated both with each other and with other cell cycle events, most notably spindle formation and anaphase chromosome segregation. In fission yeast, the CAR contains two unusual type II myosins, Myo2, encoded by the gene myo2(+), and Myp2, encoded by myp2(+). The relationship of these two proteins to each other and their relative contribution to CAR assembly and contraction is largely unknown. Here we review what is known about the role of each myosin in cytokinesis and present some new information concerning their regulation and possible physical interaction.

Item Type: Article
Additional information: 1059-910X (Print) Journal Article Research Support, Non-U.S. Gov't Review
Uncontrolled keywords: Actins/metabolism Carrier Proteins/genetics/*metabolism Cell Cycle Proteins/metabolism *Cell Division Fungal Proteins/genetics/*metabolism Gene Expression Regulation, Fungal Models, Biological *Myosin Heavy Chains *Myosin Type II *Myosin Type V Myosins/genetics/*metabolism Protein-Serine-Threonine Kinases/metabolism *Saccharomyces cerevisiae Proteins Schizosaccharomyces/*cytology/genetics/physiology *Schizosaccharomyces pombe Proteins
Subjects: Q Science
Divisions: Faculties > Science Technology and Medical Studies > School of Biosciences
Depositing User: Dan Mulvihill
Date Deposited: 01 Jun 2009 07:53
Last Modified: 30 Apr 2014 11:58
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