Jones, David Wynne, Mackie, Ian J., Gallimore, Michael J., Winter, Mark (2001) Antibodies to factor XII and recurrent fetal loss in patients with the anti-phospholipid syndrome. British Journal of Haematology, 113 . pp. 550-552. ISSN 0007-1048. E-ISSN 1365-2141. (doi:10.1046/j.1365-2141.2001.02776.x) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:89)
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Abstract
Forty female patients with either primary anti-phospholipid syndrome (n = 26) or systemic lupus erythematosus (anti-phospholipid syndrome positive) (n = 14) were investigated for levels of factor XII, the presence of lupus anticoagulant and antibodies to cardiolipin, beta 2-glycoprotein I and factor XII. Twenty-one patients had a history of recurrent fetal loss (> 2, mean = 2.6). Lupus anticoagulant positivity showed a weak association with recurrent fetal loss (odds ratio = 1.1). While there was no association between the presence of antibodies to cardiolipin or beta 2-glycoprotein I with recurrent fetal loss, antibodies to factor XII showed a strong and statistically significant association (odds ratio = 5.4, P = 0.025).
Item Type: | Article |
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DOI/Identification number: | 10.1046/j.1365-2141.2001.02776.x |
Subjects: | Q Science |
Divisions: | Divisions > Division of Natural Sciences > Biosciences |
Depositing User: | Susan Davies |
Date Deposited: | 19 Dec 2007 17:56 UTC |
Last Modified: | 09 Mar 2023 11:29 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/89 (The current URI for this page, for reference purposes) |
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