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Stemformatics: Visualisation and sharing ofstem cell gene expression

Wells, Christine A, Mosbergen, Rowland, Korn, Othmar, Choi, Jarny, Seidenman, Nick, Matigian, Nicholas A, Vitale, Alejandra M, Shepherd, Jill L (2013) Stemformatics: Visualisation and sharing ofstem cell gene expression. Stem Cell Research, 10 (3). pp. 387-395. ISSN 1873-5061. (doi:10.1016/j.scr.2012.12.003) (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:84519)

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http://dx.doi.org/10.1016/j.scr.2012.12.003

Abstract

Genome-scale technologies are increasingly adopted by the stem cell research community, because of thepotential to uncover the molecular events most informative about a stem cell state. These technologies also presentenormous challenges around the sharing and visualisation ofdata derived from different laboratories or under differentexperimental conditions. Stemformatics is an easy to use, publicly accessible portal that hosts a large collection ofexemplar stem cell data. It provides fast visualisation of gene expression across a range of mouse and human datasets, withtransparent links back to the original studies. One difficulty in the analysis of stem cell signatures is the paucity of publicpathways/gene lists relevant to stem cell or developmental biology. Stemformatics provides a simple mechanism tocreate, share and analyse gene sets, providing a repository of community-annotated stem cell gene lists that areinformative about pathways, lineage commitment, and common technical artefacts. Stemformatics can be accessed atstemformatics.org.

Item Type: Article
DOI/Identification number: 10.1016/j.scr.2012.12.003
Subjects: Q Science > Q Science (General)
Q Science > QP Physiology (Living systems) > QP506 Molecular biology
Divisions: Divisions > Division of Natural Sciences > Biosciences
Depositing User: Jill Shepherd
Date Deposited: 27 Nov 2020 21:08 UTC
Last Modified: 30 Nov 2020 15:54 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/84519 (The current URI for this page, for reference purposes)

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