Martin, Andrew K., Robinson, G., Reutens, D., Mowry, B. (2015) Common genetic risk variants are associated with positive symptoms and decision-making ability in patients with schizophrenia. Psychiatry Research, 229 (1-2). pp. 606-608. ISSN 0165-1781. (doi:10.1016/j.psychres.2015.04.045) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:79709)
| The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. | |
| Official URL: https://doi.org/10.1016/j.psychres.2015.04.045 |
Abstract
Schizophrenia is a clinically heterogeneous disorder associated with broad deficits across cognitive domains. As large genomewide association studies uncover the genetic architecture of schizophrenia, the relationship between common genetic variants and clinical and cognitive characteristics will form part of an integrative approach to understanding genetic effects on the clinical phenotype. In the current study, association between common genetic risk variants and clinical and cognitive variables was investigated. Common risk variants were associated with positive symptoms and decision-making ability from the Cambridge Gambling Task with trends in other domains.
| Item Type: | Article |
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| DOI/Identification number: | 10.1016/j.psychres.2015.04.045 |
| Uncontrolled keywords: | Article; clinical feature; cohort analysis; genetic association; genetic risk; genetic variability; heredity; human; major clinical study; mental capacity; mental task; patient decision making; phenotype; positive syndrome; priority journal; risk assessment; schizophrenia; task performance; adult; decision making; female; genetic variation; genetics; genome-wide association study; male; middle aged; neuropsychological test; procedures; psychology; risk factor; schizophrenia, Adult; Decision Making; Female; Genetic Variation; Genome-Wide Association Study; Humans; Male; Middle Aged; Neuropsychological Tests; Phenotype; Risk Factors; Schizophrenia; Schizophrenic Psychology |
| Divisions: | Divisions > Division of Human and Social Sciences > School of Psychology |
| Depositing User: | Andrew Martin |
| Date Deposited: | 05 Feb 2020 10:17 UTC |
| Last Modified: | 06 Mar 2023 12:29 UTC |
| Resource URI: | https://kar.kent.ac.uk/id/eprint/79709 (The current URI for this page, for reference purposes) |
University of Kent Author Information
Martin, Andrew K..
| Creator's ORCID: |
 https://orcid.org/0000-0001-9445-9151
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