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Neural correlates of dynamic emotion perception in schizophrenia and the influence of prior expectations

Dzafic, Ilvana, Burianová, Hana, Martin, Andrew K., Mowry, Bryan (2018) Neural correlates of dynamic emotion perception in schizophrenia and the influence of prior expectations. Schizophrenia Research, 202 . pp. 129-137. ISSN 0920-9964. (doi:10.1016/j.schres.2018.06.015) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:79698)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
https://doi.org/10.1016/j.schres.2018.06.015

Abstract

Impaired emotion perception is a well-established and stable deficit in schizophrenia; however, there is limited knowledge about the underlying aberrant cognitive and brain processes that result in emotion perception deficits. Recent influential work has shown that perceptual deficits in schizophrenia may result from aberrant precision in prior expectations, associated with disrupted activity in frontal regions. In the present study, we investigated the perception of dynamic, multisensory emotion, the influence of prior expectations and the underlying aberrant brain processes in schizophrenia. During a functional Magnetic Resonance Imaging scan, participants completed the Dynamic Emotion Perception task, which induces prior expectations with emotion instruction cues. We delineated neural responses and functional connectivity in whole-brain large-scale networks underlying emotion perception. Compared to healthy individuals, schizophrenia patients had lower accuracy specifically for emotions that were congruent with prior expectations. At the neural level, schizophrenia patients had less engagement of right inferior frontal and parietal regions, as well as right amygdala dysconnectivity during discrimination of emotions congruent with prior expectations. The results indicate that individuals with schizophrenia may have aberrant prior expectations about emotional expressions, associated with under-activity in inferior frontoparietal regions and right amygdala dysconnectivity, which results in impaired perception of emotion.

Item Type: Article
DOI/Identification number: 10.1016/j.schres.2018.06.015
Uncontrolled keywords: adult; amygdala; Article; behavior assessment; clinical article; controlled study; emotionality; expectation; female; functional magnetic resonance imaging; functional neuroimaging; human; inferior frontal gyrus; male; mental disease assessment; mental task; neurophysiology; parietal gyrus; priority journal; schizophrenia; anticipation; connectome; diagnostic imaging; emotion; facial expression; middle aged; nerve cell network; nuclear magnetic resonance imaging; parietal lobe; pathophysiology; perception; physiology; prefrontal cortex; procedures; schizophrenia, Adult; Amygdala; Anticipation, Psychological; Connectome; Emotions; Facial Expression; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Nerve Net; Parietal Lobe; Prefrontal Cortex; Schizophrenia; Social Perception
Divisions: Divisions > Division of Human and Social Sciences > School of Psychology
Depositing User: Andrew Martin
Date Deposited: 04 Feb 2020 10:49 UTC
Last Modified: 16 Feb 2021 14:10 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/79698 (The current URI for this page, for reference purposes)
Martin, Andrew K.: https://orcid.org/0000-0001-9445-9151
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