Skip to main content

Modulation of Adaptive Cognitive Control by Prefrontal High-Definition Transcranial Direct Current Stimulation in Older Adults

Gbadeyan, Oyetunde, Steinhauser, Marco, Hunold, Alexander, Martin, Andrew K., Haueisen, Jens, Meinzer, Marcus (2019) Modulation of Adaptive Cognitive Control by Prefrontal High-Definition Transcranial Direct Current Stimulation in Older Adults. The Journals of Gerontology: Series B, 74 (7). pp. 1174-1183. ISSN 1079-5014. (doi:10.1093/geronb/gbz048) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
https://doi.org/10.1093/geronb/gbz048

Abstract

OBJECTIVE: Adaptive cognitive control frequently declines in advanced age. Because high-definition transcranial direct current stimulation (HD-tDCS) of the right dorsolateral prefrontal cortex (DLPFC) improved cognitive control in young adults, we investigated if this montage can also improve cognitive control in older individuals. METHOD: In a double-blind, sham HD-tDCS controlled, cross-over design, 36 older participants received right DLPFC HD-tDCS during a visual flanker task. Conflict adaptation (CA) effects on response time (RT) and error rates (ER) assessed adaptive cognitive control. Biophysical modeling assessed the magnitude and distribution of induced current in older adults. RESULTS: Active HD-tDCS enhanced CA in older adults. However, this positive behavioral effect was limited to CA in ER. Similar to results obtained in healthy young adults, current modeling analysis demonstrated focal current delivery to the DLPFC with sufficient magnitude of the induced current to modulate neural function in older adults. DISCUSSION: This study confirms the effectiveness of HD-tDCS to modulate adaptive cognitive control in advanced age.

Item Type: Article
DOI/Identification number: 10.1093/geronb/gbz048
Uncontrolled keywords: Aging, Brain stimulation, Conflict adaptation, Dorsolateral prefrontal cortex
Divisions: Faculties > Social Sciences > School of Psychology
Depositing User: Andrew Martin
Date Deposited: 29 Jan 2020 14:41 UTC
Last Modified: 29 Jan 2020 14:41 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/79695 (The current URI for this page, for reference purposes)
Martin, Andrew K.: https://orcid.org/0000-0001-9445-9151
  • Depositors only (login required):