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Sequence Isomerism in Uniform Polyphosphoesters Programmes Self-Assembly and Folding

Appukutti, Nadeema, Serpell, Christopher J., Jones, Joseph R. (2020) Sequence Isomerism in Uniform Polyphosphoesters Programmes Self-Assembly and Folding. Chemical Communications, (56). pp. 5307-5310. ISSN 1359-7345. (doi:10.1039/D0CC01319F) (KAR id:78376)


We have adapted solid phase phosphoramidite synthesis commonly used to make DNA, to produce two sequence-isomeric non-biological polymers which display sequence-programmed folding and self-assembly, going beyond structures which would be trivially anticipated. These findings open up possibilities for more sophisticated sequence/structure relationships using the same synthetic platform.

Item Type: Article
DOI/Identification number: 10.1039/D0CC01319F
Subjects: Q Science > QD Chemistry
Divisions: Divisions > Division of Natural Sciences > Physics and Astronomy
Depositing User: Christopher Serpell
Date Deposited: 07 Nov 2019 14:28 UTC
Last Modified: 14 Nov 2022 23:10 UTC
Resource URI: (The current URI for this page, for reference purposes)

University of Kent Author Information

Serpell, Christopher J..

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