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Clinical significance of superficial vein thrombosis

Leon, L., Giannoukas, A.D., Dodd, D., Chan, P., Labropoulos, N. (2005) Clinical significance of superficial vein thrombosis. European Journal of Vascular and Endovascular Surgery, 29 (1). pp. 10-17. ISSN 1078-5884. (doi:10.1016/j.ejvs.2004.09.021) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:78334)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
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Objective. To evaluate the clinical implications of superficial thrombophlebitis (STP) including its demographic characteristics, distribution, risk factors, relationship with deep vein thrombosis (DVT), pulmonary embolism (PE), diagnosis and management. Methods. Data were collected from relevant papers using a MEDLINE search and an extensive bibliography review. Studies were considered only when they contained pertinent material to STP. Thirty-seven papers were analysed. Results. The diversity of patients and methods used in the different studies made the comparison among them difficult. STP is a common condition with an underestimated prevalence. There are many risk factors associated with STP but the strongest relation was seen with hypercoagulable states. Malignancy may be another important factor but the strength of this association remains unknown. Coexistence with DVT was found in 6-53%. PE occurred in 0-33.3%. Propagation to DVT ranged from 2.6 to 15%. Treatment has not been standardised and may include elastic compression, anti-inflammatory drugs, anticoagulation and surgery. Conclusion. The limited number of prospective randomised studies on STP does not allow strong recommendations to be given. Although STP most often is perceived as benign, it can coexist with or progress to DVT, and even give rise to PE. It is also associated with hypercoagulability and malignancy.

Item Type: Article
DOI/Identification number: 10.1016/j.ejvs.2004.09.021
Uncontrolled keywords: Duplex ultrasonography, Hypercoagulable states, Superficial vein thrombosis, Venous thromboembolism, acetylsalicylic acid, activated protein C, antibiotic agent, anticoagulant agent, antiinflammatory agent, antithrombin III, blood clotting factor 12, blood clotting factor 5 Leiden, blood clotting factor 8, blood clotting inhibitor, cardiolipin antibody, fibrinolytic factor, heparin, heparin cofactor II, hirudoid, low molecular weight heparin, nonsteroid antiinflammatory agent, oral contraceptive agent, pentasaccharide, protein C, protein S, prothrombin, sex hormone, warfarin, anticoagulant therapy, cardiovascular risk, clinical trial, comorbidity, compression, compression therapy, deep vein thrombosis, demography, diagnostic approach route, disease association, drug megadose, geographic distribution, human, hypercoagulability, lung embolism, malignant neoplastic disease, MEDLINE, peripheral vascular disease, peripheral vein, pregnancy, prevalence, priority journal, review, sclerotherapy, thrombectomy, thrombophlebitis, varicosis, vein ligation, vein stripping, vein thrombosis, Humans, Pulmonary Embolism, Risk Factors, Venous Thrombosis
Divisions: Divisions > Division of Natural Sciences > Kent and Medway Medical School
Depositing User: Philip Chan
Date Deposited: 07 Nov 2019 14:48 UTC
Last Modified: 14 Dec 2023 04:14 UTC
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