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Chronic exposure to outdoor air pollution and lung function in adults

Forbes, L.J.L., Kapetanakis, V., Rudnicka, A.R., Cook, D.G., Bush, T., Stedman, J.R., Whincup, P.H., Strachan, D.P., Anderson, H.R. (2009) Chronic exposure to outdoor air pollution and lung function in adults. Thorax, 64 (8). pp. 657-663. ISSN 0040-6376. E-ISSN 1468-3296. (doi:10.1136/thx.2008.109389) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Official URL
http://dx.doi.org/10.1136/thx.2008.109389

Abstract

Background: The extent to which chronic exposure to outdoor air pollutants influences lung function in adults is unclear. The aim of this study was to measure the association between chronic exposure to outdoor air pollutants and adult lung function.

Methods: The relationship between measures of lung function (forced expiratory volume in 1 s (FEV\(_1\)) and FEV\(_1\) as a percentage of forced vital capacity (FVC) and average exposure to particulate matter <10 μm in diameter, nitrogen dioxide, sulfur dioxide and ozone was examined in four representative cross-sectional surveys of the English population aged ⩾16 in 1995, 1996, 1997 and 2001. Year-specific estimates were pooled using fixed effects meta-analysis.

Results: Greater exposure to particulate matter <10 μm in diameter, nitrogen dioxide and sulfur dioxide was associated with lower adult FEV\(_1\). The size of the effect on population mean FEV\(_1\) was about 3% for particulate matter <10 μm, and 0.7% for nitrogen dioxide and sulfur dioxide, for a 10 μg/m3 increase in pollutant concentration. The effects were most marked in men, older adults and ex-smokers. FEV1 was not associated with ozone concentration. No associations were found between the pollutants and FEV\(_1\) as a percentage of FVC.

Conclusions: Chronic exposure to outdoor air pollution is associated with modestly reduced FEV\(_1\) in adults.

Item Type: Article
DOI/Identification number: 10.1136/thx.2008.109389
Additional information: Unmapped bibliographic data: DB - Scopus [Field not mapped to EPrints] M3 - Article [Field not mapped to EPrints]
Subjects: R Medicine
Divisions: Faculties > Social Sciences > School of Social Policy Sociology and Social Research > Centre for Health Services Studies
Depositing User: Lindsay Forbes
Date Deposited: 28 Oct 2019 19:43 UTC
Last Modified: 29 Oct 2019 14:46 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/77962 (The current URI for this page, for reference purposes)
Forbes, L.J.L.: https://orcid.org/0000-0002-4654-9520
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