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Caloric Vestibular Stimulation for the Management of Motor and Non-MotorSymptoms in Parkinson’s Disease: Intention-to-Treat Data

Wilkinson, David, Podlewska, Aleksandra, Banducci, Sarah E., Pellatt-Higgins, Tracy, Slade, Martin, Bodani, Mayur, Sakel, Mohamed, Smith, Lanty, LeWitt, Peter, Ade, Kristen and others. (2019) Caloric Vestibular Stimulation for the Management of Motor and Non-MotorSymptoms in Parkinson’s Disease: Intention-to-Treat Data. Data in Brief, 25 . Article Number 104228. ISSN 2352-3409. E-ISSN 2352-3409. (doi:10.1016/j.dib.2019.104228) (KAR id:75292)

Abstract

This report provides data related to the safety and effectiveness of repeated time-varying caloric vestibular stimulation (CVS) as a treatment for motor and non-motor features of Parkinson’s disease (PD). Forty-six subjects receiving stable anti-Parkinsonian therapy were randomized to active (n=23) or placebo (n=23) treatment arms. Subjects self-administered CVS twice-daily over a period of 8 weeks at home via a portable, pre-programmed, solid-state ThermoNeuroModulation (TNM™) device delivering continually-varying thermal waveforms through aluminium ear-probes mounted on a wearable headset. Change scores from baseline to end of treatment and to a 1-month follow-up were determined using standardized clinical measures. The data presented here report sample demographics, detailed safety data and the statistical outcomes from the intention-to-treat and modified intention-to-treat analyses. These data supplement findings of the main per protocol analysis reported in the allied article entitled, ‘Caloric Vestibular Stimulation for the Management of Motor and Non-Motor Symptoms in Parkinson’s Disease’ .

Item Type: Article
DOI/Identification number: 10.1016/j.dib.2019.104228
Uncontrolled keywords: Non-invasive brain stimulation
Subjects: B Philosophy. Psychology. Religion > BF Psychology
R Medicine
Divisions: Faculties > Social Sciences > School of Psychology
Depositing User: David Wilkinson
Date Deposited: 11 Jul 2019 11:42 UTC
Last Modified: 12 Oct 2020 13:30 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/75292 (The current URI for this page, for reference purposes)
Pellatt-Higgins, Tracy: https://orcid.org/0000-0002-2543-461X
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