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Cytoskeletal induced apoptosis in yeast.

Leadsham, Jane E., Gourlay, Campbell W. (2008) Cytoskeletal induced apoptosis in yeast. Biochimica et biophysica acta Molceular Cell Research, 1783 (7). pp. 1406-1412. ISSN 0167-4889. (doi:10.1016/j.bbamcr.2008.01.019) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:7494)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL
http://dx.doi.org/10.1016/j.bbamcr.2008.01.019

Abstract

The influence of the cytoskeleton reaches into almost every aspect of eukaryotic cell function. It is a little surprise therefore that links between the regulation of the cytoskeleton and apoptosis have been found in a variety of eukaryotic systems. Studies from yeast have made a significant contribution to this new field of research and have highlighted the importance of interactions between the cytoskeleton and mitochondria in determining cell fate. In yeast both the actin and microtubular cytoskeletons have been shown to influence mitochondrial function and the commitment to apoptosis. In this review we discuss the recent advances and speculate that apoptotic mechanisms that feed off the ability of the cytoskeleton to respond to environmental signals may represent a useful mechanism to remove weak or damaged individuals from a population.

Item Type: Article
DOI/Identification number: 10.1016/j.bbamcr.2008.01.019
Uncontrolled keywords: actin; mitochondria; yeast; apoptosis; ROS; Ras; aging; cell death; cAMP
Subjects: Q Science
Divisions: Divisions > Division of Natural Sciences > Biosciences
Depositing User: Campbell Gourlay
Date Deposited: 14 Mar 2009 10:32 UTC
Last Modified: 16 Nov 2021 09:45 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/7494 (The current URI for this page, for reference purposes)
Gourlay, Campbell W.: https://orcid.org/0000-0002-2373-6788
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