Molphy, John, Dickinson, John W., Chester, Neil, Loosemore, Mike, Whyte, Greg (2019) The Effects of Inhaled Terbutaline on 3-km Running Time-Trial Performance. International journal of sports physiology and performance, 14 (6). pp. 822-828. ISSN 1555-0265. (doi:10.1123/ijspp.2018-0633) (KAR id:72469)
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Official URL https://doi.org/10.1123/ijspp.2018-0633 |
Abstract
Terbutaline is a prohibited drug except for athletes with a therapeutic use exemption certificate; terbutaline’s effects on endurance performance are relatively unknown.
Purpose:
Eight males (24.3±2.4yrs; 77.6±8kg; 179.5±4.3cm) and eight females (22.4±3yrs; 58.6±6kg; 163±9.2cm) free from respiratory disease and illness provided written informed consent. Participants completed 3 km running time-trials on a non-motorised treadmill on three separate occasions following placebo, 2 mg or 4 mg inhaled terbutaline, in a single-blind, repeated-measures design. Urine samples (15mins post-exercise) were analysed for terbutaline concentration. Data were analysed using one-way repeated measures ANOVA, significance was set at p<0.05 for all analyses.
Results:
Therapeutic dosing of terbutaline does not lead to an improvement in 3 km running performance despite significantly increased FEV1. Our findings suggest that athletes using inhaled terbutaline at high therapeutic doses to treat asthma will not gain an ergogenic advantage during 3 km running performance.
Item Type: | Article |
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DOI/Identification number: | 10.1123/ijspp.2018-0633 |
Uncontrolled keywords: | Terbutaline, Exercise, Performance, Time-trial, Doping-control |
Subjects: | R Medicine > RC Internal medicine > RC1200 Sports medicine |
Divisions: | Divisions > Division of Natural Sciences > School of Sport and Exercise Sciences |
Depositing User: | John Dickinson |
Date Deposited: | 13 Feb 2019 13:28 UTC |
Last Modified: | 16 Feb 2021 14:02 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/72469 (The current URI for this page, for reference purposes) |
Dickinson, John W.: | ![]() |
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