Skip to main content

Synthesis of fluorescently labelled oligonucleotides and nucleic acids

Davies, M.J., Shah, A., Bruce, Ian J. (2000) Synthesis of fluorescently labelled oligonucleotides and nucleic acids. Chemical Society Reviews, 29 (2). pp. 97-107. ISSN 0306-0012. (doi:10.1039/a905230e) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1039/a905230e

Abstract

The demand for and application of fluorescently labelled nucleic acid materials are growing, driven by ventures such as the Human Genome Mapping Project and the advent of DNA-based clinical diagnostics. This article surveys the strategies that are currently available for conjugation of fluorescent molecules to oligonucleotides and nucleic acids, and demonstrates how the labelled materials have been used in new and innovative assays for probing nucleic acid structure and properties.

Item Type: Article
DOI/Identification number: 10.1039/a905230e
Subjects: Q Science
Q Science > QD Chemistry
Q Science > QD Chemistry > QD431 Organic Chemistry- Biochemistry- Proteins, peptides, amino acids
Divisions: Faculties > Sciences > School of Physical Sciences
Faculties > Sciences > School of Physical Sciences > Functional Materials Group
Depositing User: I. Bruce
Date Deposited: 01 Feb 2019 13:05 UTC
Last Modified: 30 May 2019 08:49 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/71971 (The current URI for this page, for reference purposes)
  • Depositors only (login required):