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Development and evaluation of user-tested Thai patient information leaflets for non-steroidal anti-inflammatory drugs: Effect on patients’ knowledge

Jarernsiripornkui, Narumol, Phueanpinit, Pacharaporn, Pongwecharak, Juraporn, Krska, Janet (2019) Development and evaluation of user-tested Thai patient information leaflets for non-steroidal anti-inflammatory drugs: Effect on patients’ knowledge. PLOS ONE, 14 (1). ISSN 1932-6203. (doi:10.1371/journal.pone.0210395)

Abstract

Introduction Thai patients do not routinely receive patient information leaflets (PILs) with medicines, so awareness of safety issues is low. This study aimed: i) to develop Thai PILs for NSAIDs and subject these to user-testing, and ii) to assess the potential value of PILs from the patient perspective and effect on patient knowledge. Methods Four PILs for NSAIDs were developed and subjected to multiple rounds of user-testing by the general public. Self-administered questionnaires were distributed to orthopaedic outpatients prescribed one of these NSAIDs, assessing knowledge before and after providing a PIL. The follow-up questionnaire also sought use of and views on the PILs using a visual analogue scale (VAS). Results 1,240 baseline questionnaires were completed; only 13.5% of patients had good knowledge. 688 patients returned follow-up questionnaires (55.5%), of whom75% had good knowledge. In patients completing both questionnaires, mean knowledge score increased from 6.22±1.40 to 8.42±1.41 (p<0.001). Patients with high educational levels had high baseline scores (OR = 2.728) and showed greatest improvement in knowledge (OR = 5.628). 90% (625) of follow-up respondents indicated they read all information in the PILs. All also agreed that these PILs should distributed to all patients taking NSAIDs. The median VAS score for usefulness was 9.3 (IQR 8.6–10.0. Conclusions User-testing of PILs was feasible in a Thai population and enabled the development of acceptable and desirable PILs. PILs could improve patients’ knowledge about their medicine, particularly among those with higher educational level. User-tested PILS could meet the need for more written medicine information.

Item Type: Article
DOI/Identification number: 10.1371/journal.pone.0210395
Uncontrolled keywords: medicine information; user-testing; patient information leaflet
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Faculties > Sciences > Medway School of Pharmacy
Depositing User: Janet Krska
Date Deposited: 15 Jan 2019 17:44 UTC
Last Modified: 30 May 2019 08:44 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/71653 (The current URI for this page, for reference purposes)
Krska, Janet: https://orcid.org/0000-0002-4148-5652
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