Skip to main content

Training, nutrition and exercise immunology: The use of salivary Epstein Barr Virus DNA as a marker of in vivo immunity

Chidley, Corinna (2018) Training, nutrition and exercise immunology: The use of salivary Epstein Barr Virus DNA as a marker of in vivo immunity. Doctor of Philosophy (PhD) thesis, University of Kent,. (KAR id:69956)

PDF Publisher pdf
Language: English
Download (1MB) Preview
[thumbnail of 40Training, nutrition, and exercise immunology The role of salivary Epstein-Barr.pdf]
Preview
This file may not be suitable for users of assistive technology.
Request an accessible format

Abstract

Aim: The aim of this thesis was to investigate the use of salivary Epstein-Barr virus (EBV) DNA as a marker of in vivo immunity in response to training and nutritional intervention. Methods: Initially, an assay for the detection of EBV DNA in saliva was developed which was subsequently used to detect the concentration of EBV DNA in samples collected in subsequent studies. The potential role of EBV as a predictor of URTI in response to endurance exercise are presented, along with the outcome of nutritional interventions, with chapters investigating the effects of supplementation with carbohydrate, and Chlorella pyrenoidosa. Finally, data from all four of these chapters were consolidated, and the role of salivary EBV DNA as a marker of in vivo immunity investigated. Outcome: The main finding from this thesis is that salivary EBV DNA does not appear to be a useful marker of in vivo immunity based on the present data. EBV concentration was not a predictor of URTI, nor was there a relationship between EBV concentration and SIgA concentration or secretion rate, or the absolute change or percentage change in EBV from pre-post exercise and the absolute and percentage change in SIgA concentration or secretion rate.

Item Type: Thesis (Doctor of Philosophy (PhD))
Thesis advisor: Davison, Glen
Uncontrolled keywords: Training, Nutrition, Exercise Immunology, Epstein-Barr Virus, In-vivo Immunity
Divisions: Divisions > Division of Natural Sciences > School of Sport and Exercise Sciences
SWORD Depositor: System Moodle
Depositing User: System Moodle
Date Deposited: 06 Nov 2018 15:10 UTC
Last Modified: 16 Feb 2021 13:59 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/69956 (The current URI for this page, for reference purposes)
  • Depositors only (login required):