Skip to main content

Reconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro- and microchromosomes

Damas, Joana, Kim, Jaebum, Farré, Marta, Griffin, Darren K., Larkin, Denis M. (2018) Reconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro- and microchromosomes. Genome Biology, 19 (1). Article Number 155. ISSN 1474-760X. (doi:10.1186/s13059-018-1544-8) (KAR id:69616)

PDF Publisher pdf
Language: English


Download (1MB) Preview
[thumbnail of Damas et al 2018 Genome Biology 19%2c155.pdf]
Preview
This file may not be suitable for users of assistive technology.
Request an accessible format
Official URL
https://doi.org/10.1186/s13059-018-1544-8

Abstract

Background

Here, we make use of the DESCHRAMBLER algorithm to perform the first large-scale study of ancestral chromosome structure and evolution in birds. This algorithm allows us to reconstruct the overall genome structure of 14 key nodes of avian evolution from the Avian ancestor to the ancestor of the Estrildidae, Thraupidae and Fringillidae families.

Conclusions

Analysis of these reconstructions provides important insights into the variability of rearrangement rates during avian evolution and allows the detection of patterns related to the chromosome distribution of evolutionary breakpoint regions. Moreover, the inclusion of microchromosomes in our reconstructions allows us to provide novel insights into the evolution of these avian chromosomes, specifically.

Item Type: Article
DOI/Identification number: 10.1186/s13059-018-1544-8
Uncontrolled keywords: Ancestral karyotypes, Avian, Chromosome evolution, Evolutionary breakpoint regions, Homologous synteny blocks
Subjects: Q Science > QR Microbiology
Divisions: Divisions > Division of Natural Sciences > School of Biosciences
Depositing User: Darren Griffin
Date Deposited: 17 Oct 2018 15:33 UTC
Last Modified: 16 Oct 2020 15:42 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/69616 (The current URI for this page, for reference purposes)
Farré, Marta: https://orcid.org/0000-0001-9170-5767
Griffin, Darren K.: https://orcid.org/0000-0001-7595-3226
  • Depositors only (login required):

Downloads

Downloads per month over past year