Short-Term High-Dose Vitamin C and E Supplementation Attenuates Muscle Damage and Inflammatory Responses to Repeated Taekwondo Competitions: A Randomized Placebo-Controlled Trial

Background: Exercise-induced muscle damage during intensive sport events is a very common

vitamin C and E supplementation on muscle damage, hemolysis, and inflammatory responses to

Methods: Using a randomized placebo-controlled and double-blind study design, eighteen elite

(Vit C+E; N = 9) or placebo group (PLA; N = 9). Vit C+E or PLA supplements were taken daily (Vit

before taking part in 4 consecutive TKD matches on a single day. Plasma samples were obtained

damage, hemolysis, and systemic inflammatory state.

under curve, AUC -47.0% vs. PLA, p = 0.021). Plasma creatine kinase was lower in the Vit C+E

vs. PLA, p = 0.034).

effectively attenuated exercise-induced tissue damage and inflammatory response during and after

successive TKD matches.