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Evaluating Evidence of Mechanisms in Medicine: Principles and Procedures

Parkkinen, Veli-Pekka, Wallmann, Christian, Wilde, Michael Edward, Clarke, Brendan, Illari, Phyllis, Kelly, Michael, Norell, Charles, Russo, Federica, Shaw, Beth, Williamson, Jon and others. (2018) Evaluating Evidence of Mechanisms in Medicine: Principles and Procedures. SpringerBriefs in Philosophy . Springer Netherlands ISBN 978-3-319-94609-2. E-ISBN 978-3-319-94610-8. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
https://link.springer.com/book/10.1007/978-3-319-9...

Abstract

This book is the first to develop explicit methods for evaluating evidence of mechanisms in the field of medicine. It explains why it can be important to make this evidence explicit, and describes how to take such evidence into account in the evidence appraisal process. In addition, it develops procedures for seeking evidence of mechanisms, for evaluating evidence of mechanisms, and for combining this evaluation with evidence of association in order to yield an overall assessment of effectiveness.

Evidence-based medicine seeks to achieve improved health outcomes by making evidence explicit and by developing explicit methods for evaluating it. To date, evidence-based medicine has largely focused on evidence of association produced by clinical studies. As such, it has tended to overlook evidence of pathophysiological mechanisms and evidence of the mechanisms of action of interventions.

The book offers a useful guide for all those whose work involves evaluating evidence in the health sciences, including those who need to determine the effectiveness of health interventions and those who need to ascertain the effects of environmental exposures.

Item Type: Book
Additional information: Open Access publication
Uncontrolled keywords: Evidence-based medicine Mechanisms in medicine Evaluating evidence Medical methodology Evidence hierarchy Philosophy of medicine Mechanisms in literature Mechanism hypothesis Hypothesize a mechanism evidence of mechanisms Assessing exposures evidence and status of claim. Humanities Research Evidence-Based Medicine (EBM) Molecular epidemiology ebmplus.org analogous epistemic theory external validity effects of environmental exposures Open access
Subjects: B Philosophy. Psychology. Religion > B Philosophy (General)
R Medicine > R Medicine (General)
Divisions: Faculties > Humanities > School of European Culture and Languages > Philosophy
Depositing User: Jon Williamson
Date Deposited: 23 Jul 2018 13:39 UTC
Last Modified: 01 Aug 2019 10:43 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/67932 (The current URI for this page, for reference purposes)
Williamson, Jon: https://orcid.org/0000-0003-0514-4209
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