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Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort

Jackson, Charlotte, Southern, Jo, Lalvani, Ajit, Drobniewski, Francis, Griffiths, Chris J., Lipman, Marc, Bothamley, Graham H., Deeks, Jonathan J., Imran, Ambreen, Kon, Onn Min, and others. (2018) Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort. Thorax, 74 . pp. 91-94. ISSN 0040-6376. E-ISSN 1468-3296. (doi:10.1136/thoraxjnl-2017-211124) (KAR id:67126)

Abstract

We conducted a cross-sectional analysis of baseline data from a UK cohort study which enrolled participants at risk of latent tuberculosis infection (LTBI, defined as a positive result for either of the two interferon gamma release assays). Binomial regression with a log link was used to estimate crude and adjusted prevalence ratios (PRs) and 95% CIs for the relationship between diabetes mellitus (DM) and LTBI. Adjusted for age, sex, ethnicity, body mass index and the presence of other immunocompromising conditions, DM was associated with a 15% higher prevalence of LTBI (adjusted PR=1.15, 95%?CI 1.02 to 1.30, p=0.025).

Item Type: Article
DOI/Identification number: 10.1136/thoraxjnl-2017-211124
Uncontrolled keywords: Tuberculosis; Clinical epidemiology
Subjects: H Social Sciences > HM Sociology
Divisions: Divisions > Division for the Study of Law, Society and Social Justice > School of Social Policy, Sociology and Social Research > Centre for Health Services Studies
Depositing User: Melanie Rees-Roberts
Date Deposited: 25 May 2018 10:29 UTC
Last Modified: 29 Oct 2021 14:36 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/67126 (The current URI for this page, for reference purposes)

University of Kent Author Information

Rees-Roberts, Melanie.

Creator's ORCID: https://orcid.org/0000-0002-7121-0414
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