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Phase sensitive optical coherence microscopy for photothermal imaging of gold nanorods

Dobre, George and Hu, Yong and Podoleanu, Adrian (2018) Phase sensitive optical coherence microscopy for photothermal imaging of gold nanorods. In: Podoleanu, Adrian G.H. and Bang, Ole, eds. 2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources. Proceedings of SPIE . SPIE. ISBN 978-1-5106-1674-5. E-ISBN 978-1-5106-1675-2. (doi:10.1117/12.2285816) (KAR id:67052)

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We describe a swept source based phase sensitive optical coherence microscopy (OCM) system for photothermal imaging of gold nanorods (GNR). The phase sensitive OCM system employed in the study has a displacement sensitivity of 0.17 nm to vibrations at single frequencies below 250 Hz. We demonstrate the generation of phase maps and confocal phase images. By displaying the difference between successive confocal phase images, we perform the confocal photothermal imaging of accumulated GNRs behind a glass coverslip and behind the scattering media separately. Compared with two-photon luminescence (TPL) detection techniques reported in literature, the technique in this study has the advantage of a simplified experimental setup and provides a more efficient method for imaging the aggregation of GNR. However, the repeatability performance of this technique suffers due to jitter noise from the swept laser source.

Item Type: Book section
DOI/Identification number: 10.1117/12.2285816
Uncontrolled keywords: phase sensitive, optical coherence microscopy, photothermal imaging
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: George Dobre
Date Deposited: 16 May 2018 14:47 UTC
Last Modified: 26 Jan 2020 04:11 UTC
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