Gough, Rosemarie E., Goult, Benjamin T (2018) The tale of two talins – two isoforms to fine-tune integrin signalling. FEBS Letters, 592 (12). pp. 2108-2125. ISSN 0014-5793. E-ISSN 1873-3468. (doi:10.1002/1873-3468.13081) (KAR id:66903)
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Official URL http://dx.doi.org/10.1002/1873-3468.13081 |
Abstract
Talins are cytoplasmic adapter proteins essential for integrin-mediated cell adhesion to the
actin, recruit numerous signalling molecules that mediate integrin signalling, and coordinate
containing) proteins. Vertebrates have two talin genes, TLN1 and TLN2. Although talin1 and
and the differences between the two isoforms are not fully understood. In this Review, we focus
and function, which hint at subtle differences in fine-tuning adhesion signalling.
Item Type: | Article |
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DOI/Identification number: | 10.1002/1873-3468.13081 |
Uncontrolled keywords: | talin, mechanobiology, integrin |
Subjects: | Q Science > QH Natural history > QH301 Biology |
Divisions: | Divisions > Division of Natural Sciences > School of Biosciences |
Depositing User: | Ben Goult |
Date Deposited: | 04 May 2018 11:12 UTC |
Last Modified: | 29 May 2019 20:30 UTC |
Resource URI: | https://kar.kent.ac.uk/id/eprint/66903 (The current URI for this page, for reference purposes) |
Goult, Benjamin T: | ![]() |
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