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Breast cancer in elderly women: A Cancer Research Campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone

Bates, Tom, Riley, D.L., Houghton, J., Fallowfield, L., Baum, M. (1991) Breast cancer in elderly women: A Cancer Research Campaign trial comparing treatment with tamoxifen and optimal surgery with tamoxifen alone. British Journal of Surgery, 78 (5). pp. 591-594. ISSN 0007-1323. (doi:10.1002/bjs.1800780523) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:66393)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided.
Official URL
https://doi.org/10.1002/bjs.1800780523

Abstract

Three hundred and eighty?one women with operable breast cancer aged over 70 years were randomly allocated to 40 mg tamoxifen daily and optimal surgery or to tamoxifen alone. At a median follow?up of 34 months there was no demonstrable difference in survival rate or in quality of life between the two treatment groups. More patients treated with tamoxifen alone had a subsequent change of management and this was usually an operation for local treatment failure. This progression to surgery has not been shown to be disadvantageous and the study will continue. Informed consent for randomization was difficult to obtain, leading to the exclusion of eligible patients, and it is therefore proposed to include non?randomized patients in a total cohort study.

Item Type: Article
DOI/Identification number: 10.1002/bjs.1800780523
Additional information: Unmapped bibliographic data: DB - Scopus [Field not mapped to EPrints] M3 - Review [Field not mapped to EPrints]
Divisions: Divisions > Directorate of Education > School of Education
Depositing User: Bates Tom
Date Deposited: 15 Jan 2019 15:29 UTC
Last Modified: 16 Nov 2021 10:25 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/66393 (The current URI for this page, for reference purposes)
Bates, Tom: https://orcid.org/0000-0001-5554-1945
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