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Use of a supercontinuum white light in evaluating the spectral sensitivity of the pupil light reflex

Chin, Catherine and Leick, Lasse and Podoleanu, Adrian and Lall, Gurprit S. (2018) Use of a supercontinuum white light in evaluating the spectral sensitivity of the pupil light reflex. In: Podoleanu, Adrian G.H. and Bang, Ole, eds. 2nd Canterbury Conference on OCT with Emphasis on Broadband Optical Sources. Proceedings of SPIE . SPIE. ISBN 978-1-5106-1674-5. E-ISBN 978-1-5106-1675-2. (doi:10.1117/12.2286064) (KAR id:66351)

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We assessed the spectral sensitivity of the pupillary light reflex in mice using a high power super continuum white light (SCWL) source in a dual wavelength configuration. This novel approach was compared to data collected from a more traditional setup using a Xenon arc lamp fitted with monochromatic interference filters. Irradiance response curves were constructed using both systems, with the added benefit of a two-wavelength, equivocal power, output using the SCWL. The variables applied to the light source were intensity, wavelength and stimulus duration through which the physiological output measured was the minimum pupil size attained under such conditions. We show that by implementing the SCWL as our novel stimulus we were able to dramatically increase the physiological usefulness of our pupillometry system.

Item Type: Book section
DOI/Identification number: 10.1117/12.2286064
Uncontrolled keywords: Pupil, Mouse, Super continuum, dual wavelength
Divisions: Divisions > Division of Natural Sciences > Physics and Astronomy
Divisions > Division of Natural Sciences > Medway School of Pharmacy
Depositing User: Gurprit Lall
Date Deposited: 12 Mar 2018 12:38 UTC
Last Modified: 09 Dec 2022 06:15 UTC
Resource URI: (The current URI for this page, for reference purposes)
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