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Immunodiagnostics and immunosensor design

Gubala, Vladimir and Klein, Reinhild and Templeton, Douglas M. and Schwenk, Michael (2014) Immunodiagnostics and immunosensor design. Technical report. De Gruyter 10.1515/pac-2013-1027. (doi:10.1515/pac-2013-1027) (KAR id:65467)

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This work compiles information on the principles of diagnostic immunochemical methods and the recent advances in this field. It presents an overview of modern techniques for the production of diag- nostic antibodies, their modification with the aim of improving their diagnostic potency, the different types of immunochemical detection systems, and the increasing diagnostic applications for human health that include specific disease markers, individualized diagnosis of cancer subtypes, therapeutic and addictive drugs, food residues, and environmental contaminants. A special focus lies in novel developments of immu- nosensor techniques, promising approaches to miniaturized detection units and the associated microfluidic systems. The trends towards high-throughput systems, multiplexed analysis, and miniaturization of the diag- nostic tools are discussed. It is also made evident that progress in the last few years has largely relied on novel chemical approaches.

Item Type: Monograph (Technical report)
DOI/Identification number: 10.1515/pac-2013-1027
Uncontrolled keywords: analytes; antibodies; antigens; diagnosis; enzyme-linked immunoabsorbent assay (ELISA); flu- orescence-activated cell sorting (FACS); health; immunochemistry; immunosensors; IUPAC Chemistry and Human Health Division; multiplexes
Divisions: Divisions > Division of Natural Sciences > Medway School of Pharmacy
Depositing User: Vladimir Gubala
Date Deposited: 14 Dec 2017 18:14 UTC
Last Modified: 08 Dec 2022 23:23 UTC
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