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A meta-analytical assessment of the efficacy of immediate release methylphenidate to reduce hyperactivity in children with autistic spectrum disorder (ASD)

Bratt, Alison M., Masanyero-Bennie, Bernadette, Kelley, Stephen P. (2017) A meta-analytical assessment of the efficacy of immediate release methylphenidate to reduce hyperactivity in children with autistic spectrum disorder (ASD). Journal of Pharmaceutical Sciences & Experimental Pharmacology, 1 (1). pp. 10-18. (KAR id:65038)

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Abstract

Psychostimulant medications, such as Methylphenidate (MPH) have become main stay treatments for Attention Deficit

This study performed a meta-analysis of three randomized controlled trials homogeneously measuring the effect of immediate release Methylphenidate (MPH) to reduce scores of hyperactivity in children with comorbid ADHD + ASD. The findings that IR-MPH produces an overall moderate significant benefit to reduce hyperactivity in ASD are discussed in relation to the risk/benefit question of medication use in this population.

Item Type: Article
Subjects: Q Science
Divisions: Divisions > Division of Natural Sciences > Medway School of Pharmacy
Depositing User: Alison Kelley
Date Deposited: 06 Dec 2017 15:57 UTC
Last Modified: 16 Feb 2021 13:51 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/65038 (The current URI for this page, for reference purposes)
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