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Future developments - Adaptive Optics Applied to Glaucoma Imaging

Bradu, Adrian and Chui, Taco and Costa, Christopher and Dubra, Alfredo and Hood, Donald and Kapinchev, Konstantin and Podoleanu, Adrian G.H. and Rosen, Richard B. and Wang, Jingyu and Werner, John and Zawadski, Robert (2017) Future developments - Adaptive Optics Applied to Glaucoma Imaging. In: Iester, Michele and Garway-Heath, David and Lemij, Hans, eds. Glaucoma Imaging. European Glaucoma Society, Savona, Italy, pp. 137-143. ISBN 978-88-98320-25-7. (KAR id:63585)

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Scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) have substantially advanced ophthalmic imaging by improving the transversal resolution and axial resolution beyond that which can be achieved by the fundus camera. SLO improved the transversal resolution by using a small aperture in front of the photodetector and OCT improved the axial resolution by employing principles of coherence gating. Combining the two technologies into a single instrument produces an OCT instrument with the transversal resolution of an SLO but the finer axial resolution afforded by OCT principles, typically 5-10 um or less. Transversal resolution of both SLO and OCT instruments is limited by the aberrations of the eye to more than 15 um with a pupil size of less than 3 mm. Transversal resolution in both instruments can, in principle, be improved to less than 3 um resolution by enlarging the beam diameter. In practice, this often fails due to imperfections in the crystalline lens, cornea, intraocular fluid, and tear film that disturb the wavefront, and hence distort the round uniformity of the spot illuminating the retina. Applying adaptive optics (AO) principles, aberrations of the eye can be both measured and compensated

Item Type: Book section
Subjects: Q Science > QC Physics > QC355 Optics
R Medicine
Divisions: Divisions > Division of Natural Sciences > School of Physical Sciences
Depositing User: Adrian Bradu
Date Deposited: 26 Sep 2017 23:18 UTC
Last Modified: 16 Feb 2021 13:48 UTC
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