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Candida albicans HSP12 is co-regulated by physiological CO2 and pH

Sheth, Chirag C., Mogensen, Estelle G., Fu, Man Shun, Blomfield, Ian C., Mühlschlegel, Fritz A. (2008) Candida albicans HSP12 is co-regulated by physiological CO2 and pH. Fungal Genetics and Biology, 45 (7). pp. 1075-1080. ISSN 1087-1845. (doi:10.1016/j.fgb.2008.04.004) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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Abstract

Global transcriptional analysis of Candida albicans exposed to elevated ambient CO(2) revealed a statistically significant differential regulation of 14 genes. Subsequent RNA hybridisation analysis of one gene, HSP12, confirmed CO(2)-regulation via a cAMP-dependent mechanism. Additionally, Northern analyses and gel mobility shift assays demonstrate the co-regulation of HSP12 by environmental pH via a Rim101-dependent mechanism.

Item Type: Article
DOI/Identification number: 10.1016/j.fgb.2008.04.004
Additional information: 1096-0937 (Electronic) Journal article
Uncontrolled keywords: Candida albicans; CO2; microarray; HSP12; EMSA; pH; transcriptional regulation
Subjects: Q Science
Divisions: Faculties > Sciences > School of Biosciences > Biomedical Research Group
Depositing User: F. Muhlschlegel
Date Deposited: 13 Mar 2009 10:37 UTC
Last Modified: 28 May 2019 13:41 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/6198 (The current URI for this page, for reference purposes)
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