Acute kidney injury and critical limb ischaemia associated with the use of the so called "legal high" 3-Fluorophenmetrazine

Fawzy, Michael, Wong-Morrow, Wei San, Beaumont, Anthony, Farmer, Christopher K. (2017) Acute kidney injury and critical limb ischaemia associated with the use of the so called "legal high" 3-Fluorophenmetrazine. CEN Case Reports, 6 (2). pp. 152-155. ISSN 2192-4449. (doi:10.1007/s13730-017-0263-4)

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Abstract

Until the law in the United Kingdom changed in May 2016 so called “legal highs” or “new psychoactive substances” were freely available in high street shops across the United Kingdom (UK). Following prohibition these drugs are still easily purchased illegally via the internet. We report a case of a patient who self-administered 3-Fluorophenmetrazine intravenously with catastrophic consequences. Adverse effects were almost immediate with symptoms of malaise and tachycardia. Two days post administration he was transferred to the intensive therapy unit with acute kidney injury and irreversible four limb ischaemia. He required a period of renal replacement therapy and bilateral lower limb amputation. This case highlights the fact that new psychoactive substances have many unintended adverse effect which have not been previously described. Multiple routes of administration are used by people taking these agents including intravenously. Medical practitioners should always consider ingestion of new psychoactive substances in the differential diagnosis of acutely ill patients.

Item Type: Article
DOI/Identification number: 10.1007/s13730-017-0263-4
Uncontrolled keywords: Acute Kidney Injury; New Psychoactive substance; Limb ischaemia
Subjects: R Medicine
R Medicine > RT Nursing
Divisions: Faculties > Social Sciences > School of Social Policy Sociology and Social Research
Faculties > Social Sciences > School of Social Policy Sociology and Social Research > Centre for Health Services Studies
Depositing User: Paula Loader
Date Deposited: 07 Jul 2017 15:06 UTC
Last Modified: 29 May 2019 19:05 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/61847 (The current URI for this page, for reference purposes)
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