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Toward Intraoperative Breast Endomicroscopy With a Novel Surface-Scanning Device

Zuo, Siyang, Hughes, Michael, Seneci, Carlo, Chang, Tou Pin, Yang, Guang-Zhong (2015) Toward Intraoperative Breast Endomicroscopy With a Novel Surface-Scanning Device. IEEE Transactions on Biomedical Engineering, 62 (12). pp. 2941-2952. ISSN 0018-9294. (doi:10.1109/TBME.2015.2455597) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:61183)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
https://doi.org/10.1109/TBME.2015.2455597

Abstract

New optical biopsy methods such as confocal endomicroscopy represent a promising tool for breast conserving surgery, allowing real-time assessment of tumor margins. However, it remains difficult to scan over a large surface area because of the small field-of-view. This paper presents a novel robotic instrument to perform automated scanning with a fiber bundle endomicroscope probe to expand the effective imaging area. The device uses a rigid concentric tube scanning mechanism to facilitate large-area mosaicking. It has a compact design with a diameter of 6 mm, incorporating a central channel with a diameter of 3 mm for passing through a fiber bundle probe. A bespoke bearing, an inflated balloon, and a passive linear structure are used to control image rotation and ensure consistent tool-tissue contact. Experimental results show that the device is able to scan a spiral trajectory over a large hemispherical surface. Detailed performance evaluation was performed and the bending angle ranges from -90° to 90° with high repeatability and minimal rotational hysteresis errors. The device has also been validated with breast phantom and ex vivo human breast tissue, demonstrating the potential clinical value of the system.

Item Type: Article
DOI/Identification number: 10.1109/TBME.2015.2455597
Divisions: Faculties > Sciences > School of Physical Sciences
Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Michael Hughes
Date Deposited: 06 Apr 2017 14:01 UTC
Last Modified: 01 Aug 2019 10:41 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/61183 (The current URI for this page, for reference purposes)
Hughes, Michael: https://orcid.org/0000-0001-5301-2492
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