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Validation of an instrument to measure patients' experiences of medicine use: the Living with Medicines Questionnaire

Krska, Janet, Katusiime, Barbra, Corlett, Sarah A. (2017) Validation of an instrument to measure patients' experiences of medicine use: the Living with Medicines Questionnaire. Patient Preference and Adherence, 2017 (11). pp. 671-679. ISSN 1177-889X. (doi:10.2147/PPA.S126647) (KAR id:61096)

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Background: Medicine-related burden is an increasingly recognised concept, stemming from the rising tide of polypharmacy, which may impact on patient behaviours, including non-adherence. No instruments currently exist which specifically measure medicine-related burden. The Living with Medicines Questionnaire was developed for this purpose.

Methods: Questionnaires were distributed in community pharmacies and public places in south-east England, or online via UK health websites and social media. A total of 1177 were returned 507 (43.1%) from pharmacy distribution and 670 (56.9%) on-line. Construct validity was assessed by principal components analysis and item reduction undertaken on the original 60-item pool. Known-groups analysis assessed differences in mean total scores between participants using different numbers of medicines and those requiring assistance with medicine use. Internal consistency was assessed by Cronbach’s alpha. Free-text comments were analysed thematically to substantiate underlying dimensions.

Conclusions: The resultant Living with Medicines Questionnaire (LMQ-2) is a valid and reliable multidimensional measure of prescription medicine use experiences, which covers more diverse domains than existing questionnaires. However, further validation work is necessary.

Item Type: Article
DOI/Identification number: 10.2147/PPA.S126647
Uncontrolled keywords: medicines, polypharmacy, patient experience, questionnaire, validation, Medway School of Pharmacy
Subjects: R Medicine
Divisions: Divisions > Division of Natural Sciences > Medway School of Pharmacy
Depositing User: Janet Krska
Date Deposited: 30 Mar 2017 11:13 UTC
Last Modified: 16 Feb 2021 13:44 UTC
Resource URI: (The current URI for this page, for reference purposes)
Krska, Janet:
Corlett, Sarah A.:
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