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Developing a conceptual framework for an evaluation system for the NIAID HIV/AIDS clinical trials networks

Kagan, Jonathan M., Kane, Mary, Quinlan, Kathleen M., Rosas, Scott, Trochim, William M.K. (2009) Developing a conceptual framework for an evaluation system for the NIAID HIV/AIDS clinical trials networks. Health Research Policy and Systems, 7 . ISSN 1478-4505. E-ISSN 1478-4505. (doi:10.1186/1478-4505-7-12) (KAR id:60292)


Globally, health research organizations are called upon to re-examine their policies and practices to more efficiently and effectively address current scientific and social needs, as well as increasing public demands for accountability. Through a case study approach, the authors examine an effort undertaken by the National Institute of Allergy & Infectious Diseases (part of the National Institutes of Health, Department of Health & Human Services, United States Government) to develop an evaluation system for its recently restructured HIV/AIDS clinical trials program. The challenges in designing, operationalizing, and managing global clinical trials programs are considered in the context of large scale scientific research initiatives. Through a process of extensive stakeholder input, a framework of success factors was developed that enables both a prospective view of the elements that must be addressed in an evaluation of this research and a current state assessment of the extent to which the goals of the restructuring are understood by stakeholders across the DAIDS clinical research networks.

Item Type: Article
DOI/Identification number: 10.1186/1478-4505-7-12
Uncontrolled keywords: acquired immune deficiency syndrome, clinical protocol, clinical research, conceptual framework, drug research, evaluation research, Human immunodeficiency virus infection, infection prevention, national health organization, organizational restructuring, participatory management, professional standard, program development, research ethics, research priority, review, virus transmission
Subjects: R Medicine
Divisions: Divisions > Directorate of Education > Centre for the Study of Higher Education
Depositing User: Kathleen Quinlan
Date Deposited: 10 Feb 2017 16:15 UTC
Last Modified: 16 Nov 2021 10:24 UTC
Resource URI: (The current URI for this page, for reference purposes)

University of Kent Author Information

Quinlan, Kathleen M..

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