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Impaired Blood Neutrophil Function in the Frequent Exacerbator of Chronic Obstructive Pulmonary Disease: A Proof-of-Concept Study

Jones, Arwel Wyn, Robinson, Richard, Mohamed, Peer, Davison, Glen, Izzat, Hassan Jaysen, Lewis, Keir Edward (2016) Impaired Blood Neutrophil Function in the Frequent Exacerbator of Chronic Obstructive Pulmonary Disease: A Proof-of-Concept Study. Lung, 194 (6). pp. 881-887. ISSN 0341-2040. E-ISSN 1432-1750. (doi:10.1007/s00408-016-9930-z) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided) (KAR id:59957)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1007/s00408-016-9930-z

Abstract

Purpose

Whole blood from COPD frequent exacerbators (defined as ?2 moderate–severe exacerbations in the previous 2 years) and non-exacerbators (no exacerbations in the preceding 2 years) was assayed for neutrophil function. Neutrophil function in healthy ex-smoking volunteers was also measured as a control (reference) group.

Results

This study is the first to report aberrant receptor-mediated blood neutrophil function in the frequent exacerbator of COPD.

Item Type: Article
DOI/Identification number: 10.1007/s00408-016-9930-z
Divisions: Divisions > Division of Natural Sciences > School of Sport and Exercise Sciences
Depositing User: Glen Davison
Date Deposited: 20 Jan 2017 12:39 UTC
Last Modified: 16 Feb 2021 13:41 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/59957 (The current URI for this page, for reference purposes)
Davison, Glen: https://orcid.org/0000-0003-4340-0074
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