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Symptom Control and Adherence are Major Issues for Asthmatic Patients: Can they be Improved and are They Linked?

Manfrin, Andrea (2016) Symptom Control and Adherence are Major Issues for Asthmatic Patients: Can they be Improved and are They Linked? Ministry of Health, Rome (Access to this publication is currently restricted. You may be able to access a copy if URLs are provided) (KAR id:59377)

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A cluster randomized controlled trial involving 15 out of the 20 Italian regions was conducted between September 2014 and July 2015 with data collection before, during and after pharmacists’ intervention; every 3 months (T0, T3, T6, T9). Pharmacists were randomly allocated to different groups after stratification by region: A (n=104) were trained to provide the Italian Medicines Use review (I-MUR) immediately after completion of the baseline Asthma Control TestTM (ACT) score; B (n=112) received training and provided this service 3 months later. The primary outcome measure was asthma control, assessed using the ACT scores, before and after the I-MUR intervention, defined by the international guidelines (ACT?19 = not controlled; ACT ?20 = controlled). Secondary outcome was adherence to treatment before and after the intervention assessed using the Morisky scale.

Pharmacists in group A recruited 428 patients and in group B, 456. Patients were well distributed among regions; the percentage of female was 58.6%. Baseline ACT score showed that 56% of patients had asthma not fully controlled.



2 Vervloet D, Willians A. E., Llyod A., Clark T.J.H. Costs of managing asthma as defined by a derived Asthma Control Test score in seven European countries. Eur. Respir Rev 2006; 15:98, 17-23

4 Manfrin A, Thomas T, Krska J. Randomised evaluation of the Italian medicines use review provided by community pharmacists using asthma as a model (RE I-MUR). BMC Health services research (2015) 15:171

Item Type: Book
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Divisions > Division of Natural Sciences > Medway School of Pharmacy
Depositing User: Andrea Manfrin
Date Deposited: 02 Dec 2016 12:01 UTC
Last Modified: 16 Feb 2021 13:40 UTC
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Manfrin, Andrea:
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