The Effect of Lateralization of Motor Onset and Emotional Recognition in PD Patients Using EEG

Yuvaraj, Rajamanickam and Murugappan, Murugappan and Palaniappan, Ramaswamy (2016) The Effect of Lateralization of Motor Onset and Emotional Recognition in PD Patients Using EEG. Brain Topography, . pp. 1-10. ISSN 0896-0267. E-ISSN 1573-6792. (doi:https://doi.org/10.1007/s10548-016-0524-0) (Full text available)

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http://dx.doi.org/10.1007/s10548-016-0524-0

Abstract

The objective of this research was to investigate the relationship between emotion recognition and lateralization of motor onset in Parkinson’s disease (PD) patients using electroencephalogram (EEG) signals. The subject pool consisted of twenty PD patients [ten with predominantly leftsided (LPD) and ten with predominantly rightsided (RPD) motor symptoms] and 20 healthy controls (HC) that were matched for age and gender. Multimodal stimuli were used to evoke simple emotions, such as happiness, sadness, fear, anger, surprise, and disgust. Artifactfree emotion EEG signals were processed using the auto regressive spectral method and then subjected to repeated ANOVA measures. No group differences were observed across behavioral measures; however, a significant reduction in EEG spectral power was observed at alpha, beta and gamma frequency oscillations in LPD, compared to RPD and HC participants, suggesting that LPD patients (inferred righthemisphere pathology) are impaired compared to RPD patients in emotional processing. We also found that PD related emotional processing deficits may be selective to the perception of negative emotions. Previous findings have suggested a hemispheric effect on emotion processing that could be related to emotional response impairment in a subgroup of PD patients. This study may help in clinical practice to uncover potential neurophysiologic abnormalities of emotional changes with respect to PD patient’s motor onset.

Item Type: Article
Uncontrolled keywords: EEG; Emotion; Parkinson’s disease; Body side of motor onset
Subjects: Q Science > QA Mathematics (inc Computing science)
R Medicine > R Medicine (General)
Divisions: Faculties > Sciences > School of Computing
Depositing User: Palaniappan Ramaswamy
Date Deposited: 22 Sep 2016 15:05 UTC
Last Modified: 23 Sep 2017 23:00 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/57443 (The current URI for this page, for reference purposes)
Palaniappan, Ramaswamy: https://orcid.org/0000-0001-5296-8396
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