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The mRNA cap-binding protein eIF4E in post-transcriptional gene expression

von der Haar, Tobias, Gross, John D., Wagner, Gerhard, McCarthy, John E. G. (2004) The mRNA cap-binding protein eIF4E in post-transcriptional gene expression. Nature Structural and Molecular Biology, 11 (6). pp. 503-511. ISSN 1545-9985. (doi:10.1038/nsmb779) (KAR id:5337)

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Official URL:
http://dx.doi.org/10.1038/nsmb779

Abstract

Eukaryotic initiation factor 4E (eIF4E) has central roles in the control of several aspects of post-transcriptional gene expression and thereby affects developmental processes. It is also implicated in human diseases. This review explores the relationship between structural, biochemical and biophysical aspects of eIF4E and its function in vivo, including both long-established roles in translation and newly emerging ones in nuclear export and mRNA decay pathways.

Item Type: Article
DOI/Identification number: 10.1038/nsmb779
Subjects: Q Science
Divisions: Divisions > Division of Natural Sciences > Biosciences
Depositing User: Tobias von der Haar
Date Deposited: 09 Sep 2008 15:12 UTC
Last Modified: 16 Nov 2021 09:43 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/5337 (The current URI for this page, for reference purposes)

University of Kent Author Information

von der Haar, Tobias.

Creator's ORCID: https://orcid.org/0000-0002-6031-9254
CReDIT Contributor Roles:
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