Skip to main content

Transcranial direct current stimulation (tDCS) of the left dorsolateral prefrontal cortex modulates declarative memory.

Javadi, Amir-Homayoun, Walsh, Vincent (2012) Transcranial direct current stimulation (tDCS) of the left dorsolateral prefrontal cortex modulates declarative memory. Brain stimulation, 5 (3). pp. 231-41. ISSN 1935-861X. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://www.ncbi.nlm.nih.gov/pubmed/21840287

Abstract

BACKGROUND: Previous studies have claimed that weak transcranial direct current stimulation (tDCS) induces persisting activity changes in the human motor cortex and working memory, but to date no studies have evaluated the effects of tDCS on declarative memory. OBJECTIVE: Our aim was to determine whether anodal and cathodal transcranial direct current stimulation would differentially modify performance in a word memorization task during encoding or recognition when administered over the left dorsolateral prefrontal cortex (DLPFC). METHODS: In two experiments, 32 participants underwent a series of word memorization tasks. This task was performed during sham, anodal, and cathodal stimulation applied over the left DLPFC. Moreover, participants in the first experiment performed the same task with anodal tDCS of the primary motor cortex (M1). RESULTS: During encoding, anodal stimulation of the left DLPFC improved memory, whereas cathodal stimulation of the same area impaired memory performance in later recognition. Anodal stimulation of M1 had no effect on later recognition. During recognition cathodal stimulation of the left DLPFC impaired recognition compared with sham stimulation of the same area and anodal stimulation had a trend toward improving the recognition. CONCLUSIONS: The results indicated that active stimulation of the left DLPFC leads to an enhancement or impairment of verbal memorization depending on the polarity of the stimulation. Furthermore, this effect was specific to the site of stimulation.

Item Type: Article
Uncontrolled keywords: DLPFC,declarative memory,dorsolateral prefrontal cortex,electrical brain stimulation,tDCS
Subjects: B Philosophy. Psychology. Religion > BF Psychology
Divisions: Faculties > Social Sciences > School of Psychology > Cognitive Psychology
Depositing User: Amir-Homayoun Javadi
Date Deposited: 03 Dec 2015 10:41 UTC
Last Modified: 29 May 2019 16:34 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/52619 (The current URI for this page, for reference purposes)
Javadi, Amir-Homayoun: https://orcid.org/0000-0003-0569-6441
  • Depositors only (login required):