Transcranial direct current stimulation (tDCS) enhances reconsolidation of long-term memory.

Javadi, Amir-Homayoun and Cheng, Paul (2013) Transcranial direct current stimulation (tDCS) enhances reconsolidation of long-term memory. Brain stimulation, 6 (4). pp. 668-74. ISSN 1935-861X. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://www.ncbi.nlm.nih.gov/pubmed/23137702

Abstract

A new and weak memory trace undergoes consolidation to gain resistance against interfering stimuli. When an encoded memory is recalled, it becomes labile and another round of consolidation, or reconsolidation, is required to restore its stability. Transcranial direct current stimulation (tDCS) is a non-invasive method of altering cortical excitability. The aim of this study was to examine the effects of tDCS on the reconsolidation of long-term verbal memory. Participants (n = 15) memorized words in the encoding session, then reactivated the memory of the words 3 h later using an old-new recognition task under anodal, cathodal and sham stimulation to the left dorsolateral prefrontal cortex (DLPFC). Finally, after another 5 h, they performed another round of the old-new recognition task and rated their confidence. Anodal tDCS during the second session resulted in significantly more words recognized in the third session as compared to cathodal and sham stimulation. Cathodal tDCS did not affect the recognition performance compared to sham stimulation. These results cannot be attributed to differences in response times and confidence ratings, as they were comparable in all conditions. In order to study whether the activation of a memory was crucial for the enhancing effects of anodal tDCS, a group of controls (n = 15) did not perform the recognition task in the second session but still underwent stimulation. Contrary to the main group, anodal stimulation did not enhance the memory performance for the control group. This result suggests that anodal tDCS over the left DLPFC can enhance the reconsolidation of long-term memory only when the memory has been reactivated.

Item Type: Article
Uncontrolled keywords: Declarative memory,Dorsolateral prefrontal cortex (DLPFC),Electrical brain stimulation,Long-term memory,Reactivation,Reconsolidation,Transcranial direct current stimulation (tDCS)
Subjects: B Philosophy. Psychology. Religion > BF Psychology
Divisions: Faculties > Social Sciences > School of Psychology > Cognitive Psychology
Depositing User: Amir-Homayoun Javadi
Date Deposited: 03 Dec 2015 11:27 UTC
Last Modified: 07 Dec 2015 12:34 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/52607 (The current URI for this page, for reference purposes)
Javadi, Amir-Homayoun: https://orcid.org/0000-0003-0569-6441
  • Depositors only (login required):