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Correlation of quantitative light-induced fluorescence and optical coherence tomography applied for detection and quantification of early dental caries

Amaechi, Bennett T., Podoleanu, A.Gh., Higham, Susan M., Jackson, David A. (2003) Correlation of quantitative light-induced fluorescence and optical coherence tomography applied for detection and quantification of early dental caries. Journal of Biomedical Optics, 8 (4). pp. 642-647. ISSN 1083-3668. (doi:10.1117/1.1606685) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://www.dx.doi.org/10.1117/1.1606685

Abstract

Fluorescence loss in enamel following demineralization has been correlated with the amount of mineral lost during the demineralization. The correlation between fluorescence loss measured by quantitative light-induced fluorescence (QLF) and the reflectivity loss measured by a versatile en face optical coherence tomography (OCT) system was investigated in a demineralization process to produce artificial dental caries. We used an OCT system that can collect A-scans (reflectivity versus depth), B-scans (longitudinal images), and C-scans (en face images). The power to the sample was 250 μW, the wave-length λ = 850 nm, and the depth resolution in air 16 μm. A-scans, which show the profile of the reflectivity versus the depth of penetration into the tooth tissue, were used for quantitative analysis of the reflectivity loss. The results have shown that both the fluorescence radiance and reflectivity of the enamel decrease with increasing demineralization time. A linear correlation was observed between the percentage of fluorescence loss measured by QLF and the percentage of reflectivity loss measured by OCT. It was concluded that the decrease in reflectivity of the enamel during demineralization, measured by OCT, could be related to the amount of mineral lost during the demineralization process © 2003 Society of Photo-Optical Instrumentation Engineers.

Item Type: Article
DOI/Identification number: 10.1117/1.1606685
Additional information: This is available as OPEN ACCESS by clicking on the URL.
Uncontrolled keywords: Caries diagnosis, Confocal imaging, Dental caries, Dental imaging, Low coherence interferometry, Optical coherence tomography, Quantitative light-induced fluorescence, Demineralization, Dental caries, Quantitative light induced fluorescence (QLF), Reflectivity loss, Coherent light, Dentistry, Fluorescence, Medical imaging, Optical correlation, Tissue, Tooth enamel, Tomography, algorithm, animal, article, cattle, computer assisted diagnosis, confocal microscopy, dental caries, evaluation, fluorescence microscopy, image enhancement, image subtraction, in vitro study, incisor, methodology, optical coherence tomography, pathology, reproducibility, sensitivity and specificity, Algorithms, Animals, Cattle, Dental Caries, Image Enhancement, Image Interpretation, Computer-Assisted, Incisor, Microscopy, Confocal, Microscopy, Fluorescence, Reproducibility of Results, Sensitivity and Specificity, Subtraction Technique, Tomography, Optical Coherence
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 27 Jul 2015 09:18 UTC
Last Modified: 29 May 2019 14:55 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49795 (The current URI for this page, for reference purposes)
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