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Combined confocal/ en face optical coherence tomography imaging of the human eye fundus in vivo in the 1050 nm spectral region

Cucu, Radu G. and Rogers, John A. and Hathaway, Mark W. and Pedro, Justin and Podoleanu, Adrian Gh. and Rosen, Richard B. (2007) Combined confocal/ en face optical coherence tomography imaging of the human eye fundus in vivo in the 1050 nm spectral region. In: Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XI. Proceedings of SPIE . SPIE. ISBN 0-8194-6542-9. (doi:10.1117/12.704320) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1117/12.704320

Abstract

The 1020-1080 nm spectral region appears as a viable alternative to the 700-900 nm spectral band for in vivo eye fundus OCT imaging due to a local absorption minimum of water (main constituent of the eye aqueous and vitreous). Light at these wavelengths also experiences less attenuation due to lower scattering and absorption by melanin in the retinal pigment epithelium and choroid, which results in deeper penetration of the probe beam in the choroid. T-scan based en face OCT is a modification of the OCT technique that has the unique capability of acquiring both longitudinal (B-scans) and tranversal (C-scans) OCT images of the eye fundus in real time and allows the addition of a confocal scanning ophthalmoscope channel to the OCT instrument. We report for the first time a combined T-scan based en face OCT and confocal scanning opthalmoscopy system for imaging the human eye fundus in vivo in the 1050 nm region. The instrument allows the visualization of choroidal blood vessels in both the confocal and OCT channels without the use of contrast agents such as indocyanine green (ICG) dye and could prove an alternative tool for diagnosing eye conditions like age related macular degeneration that are preceded by choroidal neovascularisation.

Item Type: Book section
DOI/Identification number: 10.1117/12.704320
Uncontrolled keywords: Choroidal vascularisation; Combined confocal scanning opthalmoscopy/ en face OCT; Enhanced penetration in the choroid; Eye fundus imaging
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 24 Jul 2015 14:06 UTC
Last Modified: 26 Jul 2019 11:43 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49741 (The current URI for this page, for reference purposes)
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