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Versatile confocal/optical coherence tomography system for embryonic developmental imaging

Bradu, A. and Ma, L. and Bloor, J. and Podoleanu, A. (2008) Versatile confocal/optical coherence tomography system for embryonic developmental imaging. In: Coherence Domain Optical Methods and Optical Coherence Tomography in Biomedicine XII. Proceedings of SPIE . SPIE. ISBN 978-0-8194-7022-5. (doi:10.1117/12.765824) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1117/12.765824

Abstract

An Optical Coherence Tomography (OCT) imaging system has been designed and constructed to acquire images of scattering biological samples. By simultaneously acquiring and displaying high resolution en-face (C-scan) OCT and Laser Scanning Confocal images of Drosophila melanogaster embryos we demonstrate the potential of the system to be used as a powerful tool for imaging in Drosophila embryonic development. The system can equally be used for non invasive visualizations and measurements of the movement of Drosophila melanogaster larval heart and can easily be switched in the OCT B-scan regime. The confocal channel adds guidance as the specimen can be quickly located and this makes the use of the system in a large scale gene screen feasible.

Item Type: Book section
DOI/Identification number: 10.1117/12.765824
Uncontrolled keywords: developmental biology; Drosophila melanogaster; embryos; imaging; larvae; Laser scanning microscopy; Optical coherence tomography
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 24 Jul 2015 13:42 UTC
Last Modified: 26 Jul 2019 11:29 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49727 (The current URI for this page, for reference purposes)
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