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Direct corneal elevation measurements using multiple delay en face optical coherence tomography

Plesea, Lucian, Podoleanu, Adrian G.H. (2008) Direct corneal elevation measurements using multiple delay en face optical coherence tomography. Journal of Biomedical Optics, 13 (5). p. 2993161. ISSN 1083-3668. (doi:10.1117/1.2993161) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1117/1.2993161

Abstract

Optical coherence tomography (OCT) is a well-established imaging method in the ophthalmic practice. We describe a novel corneal topography method that directly measures anterior cornea surface elevation from a single en face OCT image. This method uses an OCT interferometer configuration equipped with a multiple delay element (MDE) in the reference arm. The MDE selects multiple axial positions within the target object, simultaneously, which leads to information from multiple axial distances to be cumulated in a single en face OCT frame. When an en face OCT scan of a cornea is acquired with such an OCT setup, the resulting image contains nonoverlapping circular contours. Images of a reflective metallic sphere obtained using this method are used to numerically calibrate the setup. Using these calibration results, position information contained in the en face images from the cornea can be measured directly obtaining three-dimensional coordinates for multiple points located on the cornea surface. From these points, the topographic map of the anterior cornea surface can be generated, using interpolation or Zernike polynomial decomposition. Experimental results of in vivo cornea topography obtained with this method are presented.

Item Type: Article
DOI/Identification number: 10.1117/1.2993161
Uncontrolled keywords: C-scan, corneal topography, en face, in vivo imaging, multiple delay element, optical coherence tomography, C-scan, corneal topography, en face, In-Vivo imaging, Multiple delays, Maps, Spheres, Surface topography, Tomography, Topography, Three dimensional, algorithm, article, computer assisted diagnosis, cornea, evaluation, histology, human, image enhancement, instrumentation, keratometry, methodology, optical coherence tomography, physiology, reproducibility, sensitivity and specificity, three dimensional imaging, Algorithms, Cornea, Corneal Topography, Humans, Image Enhancement, Image Interpretation, Computer-Assisted, Imaging, Three-Dimensional, Reproducibility of Results, Sensitivity and Specificity, Tomography, Optical Coherence
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 24 Jul 2015 11:27 UTC
Last Modified: 29 May 2019 14:54 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49707 (The current URI for this page, for reference purposes)
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