Black cohosh improves objective sleep in postmenopausal women with sleep disturbance

Jiang, K and Jin, Y and Huang, L and Feng, S and Hou, X and Du, B and Zheng, J and Li, Ling (2015) Black cohosh improves objective sleep in postmenopausal women with sleep disturbance. Climacteric, 18 (4). pp. 559-567. ISSN 1369-7137. (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

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http://informahealthcare.com/doi/abs/10.3109/13697...

Abstract

Objective Sleep problems are prominent after menopause. The aim of our study was to look into the effect of black cohosh on both objective and subjective sleep in early postmenopausal women with sleep complaints. Methods We performed a randomized, double-blind and placebo-controlled research during a 6-month period. Forty-eight postmenopausal women aged 45–60 years with sleep disturbance were enrolled and received daily administration of either black cohosh or placebo. Polysomnography and the Pittsburg Sleep Quality Index (PSQI) were performed at the initiation and termination of the study, as well as the Menopause-specific Quality of Life questionnaire and estradiol and follicle stimulating hormone tests. Liver and renal functions and breast and pelvic ultrasound were set as safety measures, carried out every 3 months. Results Seventy-six women were interviewed, of whom 42 women completed the whole trial. Compared with placebo, black cohosh treatment led to significant polysomnographic changes, including increased sleep efficiency and decreased wake after sleep onset (WASO) duration, and tended to improve PSQI with a medium effect size. On average, 15.8% of WASO duration was reduced in the black cohosh group. Vasomotor and physical domains of life quality were improved compared with placebo. Safety measures did not yield any adverse event assigned to black cohosh. Conclusions In early postmenopausal women with a major sleep complaint, black cohosh effectively improved sleep and might be a safe measure in managing menopausal sleep disturbance.

Item Type: Article
Projects: Projects 10226 not found.
Uncontrolled keywords: BLACK COHOSH, POSTMENOPAUSAL, POLYSOMNOGRAPHY, SLEEP
Subjects: R Medicine > R Medicine (General) > R858 Medical informatics
Divisions: Faculties > Sciences > School of Computing > Computational Intelligence Group
Faculties > Sciences > School of Computing > Data Science
Depositing User: Caroline Li
Date Deposited: 17 Jul 2015 15:05 UTC
Last Modified: 22 Jul 2015 08:22 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49587 (The current URI for this page, for reference purposes)
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