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Multidimensional en-Face OCT imaging of the retina

Rosen, R.B., Hathaway, M., Rogers, J., Pedro, J., Garcia, P., Laissue, P., Dobre, George, Podoleanu, A.Gh. (2009) Multidimensional en-Face OCT imaging of the retina. Optics Express, 17 (5). pp. 4112-4133. ISSN 1094 4087. E-ISSN 1094-4087. (doi:10.1364/OE.17.004112) (The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided)

The full text of this publication is not currently available from this repository. You may be able to access a copy if URLs are provided. (Contact us about this Publication)
Official URL
http://dx.doi.org/10.1364/OE.17.004112

Abstract

Fast T-scanning (transverse scanning, en-face) was used to build B-scan or C-scan optical coherence tomography (OCT) images of the retina. Several unique signature patterns of en-face (coronal) are reviewed in conjunction with associated confocal images of the fundus and B-scan OCT images. Benefits in combining T-scan OCT with confocal imaging to generate pairs of OCT and confocal images similar to those generated by scanning laser ophthalmoscopy (SLO) are discussed in comparison with the spectral OCT systems. The multichannel potential of the OCT/SLO system is demonstrated with the addition of a third hardware channel which acquires and generates indocyanine green (ICG) fluorescence images. The OCT, confocal SLO and ICG fluorescence images are simultaneously presented in a two or a three screen format. A fourth channel which displays a live mix of frames of the ICG sequence superimposed on the corresponding coronal OCT slices for immediate multidimensional comparison, is also included. OSA ISP software is employed to illustrate the synergy between the simultaneously provided perspectives. This synergy promotes interpretation of information by enhancing diagnostic comparisons and facilitates internal correction of movement artifacts within C-scan and B-scan OCT images using information provided by the SLO channel. © 2009 Optical Society of America.

Item Type: Article
DOI/Identification number: 10.1364/OE.17.004112
Additional information: This is available as OPEN ACCESS by clicking on the URL.
Uncontrolled keywords: Coherent light, Diagnostic radiography, Fluorescence, Internet service providers, Tomography, Confocal images, Confocal imaging, Fluorescence images, Indocyanine greens, Movement artifacts, Multichannel, OCT imaging, Optical-coherence tomographies, Scanning laser ophthalmoscopies, Spectral OCT, Scanning, diagnostic agent, fluorescent dye, indocyanine green, article, comparative study, diabetic retinopathy, equipment design, evaluation, eye fundus, histology, human, image processing, instrumentation, laser, light related phenomena, methodology, ophthalmoscope, ophthalmoscopy, optical coherence tomography, pathology, retina, retina disease, statistics, subretinal neovascularization, Choroidal Neovascularization, Diabetic Retinopathy, Equipment Design, Fluorescent Dyes, Fundus Oculi, Humans, Image Processing, Computer-Assisted, Indocyanine Green, Lasers, Ophthalmoscopes, Ophthalmoscopy, Optical Phenomena, Retina, Retinal Diseases, Tomography, Optical Coherence
Subjects: Q Science > QC Physics
R Medicine > R Medicine (General) > R857.O6 Optical coherence tomography
Divisions: Faculties > Sciences > School of Physical Sciences > Applied Optics Group
Depositing User: Giles Tarver
Date Deposited: 14 Jul 2015 15:29 UTC
Last Modified: 01 Aug 2019 10:39 UTC
Resource URI: https://kar.kent.ac.uk/id/eprint/49473 (The current URI for this page, for reference purposes)
Dobre, George: https://orcid.org/0000-0002-5695-2591
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